Search on: HETERODIMER, KU 
Descriptors Found: 1
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Descriptor English:   Ku Autoantigen 
Descriptor Spanish:   Autoantígeno Ku 
Descriptor Portuguese:   Autoantígeno Ku 
Synonyms English:   G22P1 Antigen
Ku Antigen
Ku Autoantigen, 70 kDa
Ku Autoantigen, 80 kDa
Ku Heterodimer
Ku Protein
Ku70 Antigen
Ku80 Antigen
X-ray Repair Cross-Complementing Protein 5
X-ray Repair Cross-Complementing Protein 6
XRCC5 Protein
XRCC6 Protein
Antigen, G22P1
Antigen, Ku
Antigen, Ku70
Antigen, Ku80
Autoantigen, Ku
Heterodimer, Ku
X ray Repair Cross Complementing Protein 5
X ray Repair Cross Complementing Protein 6  
Tree Number:   D08.811.277.040.025.159.155
D08.811.399.340.155
D12.776.157.687.493
D12.776.260.525
D12.776.660.625.625
D12.776.660.720.493
D23.050.290.625
Definition English:   An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION. 
History Note English:   2017 (1986) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56468 
Unique Identifier:   D000072200 

Occurrence in VHL: 		 

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